Deuterium oxide MSDS

SAFETY DATA SHEET

according to the Global Harmonized System

Version: GHS 1

 

1. Identification of the substance/mixture and of the company/undertaking

 

DEUTERIUM OXIDE	Product name
1.004.025, 1.004.050 1.031.050 1.032.050 1.033.025, 1.033.050	(Cat. No.(s
Laboratory chemicals, Manufacture of substances	Identified uses
Mesbah Energy Co Arak Science & Technology Park Shahid Ghoddousi Blvd., Arak, Iran Tel-Fax: [phone] Email: [e-mail]	company/undertaking Identification

 

2. Hazards identification

 

No data available	Classification of the substance or mixture
No data available	Label elements
No data available	Other hazards

 

3. Composition/information on ingredients

 

Heavy water, Water-d2	Substances synonyms
D2O	Formula
7789-20-0	.CAS NO

 

4. First aid measures

 

Consult a physician. Show this safety data sheet to the doctor in attendance. Move out of dangerous area	General
If breathed in, move person to fresh air. If not breathing, give artificial respiration. Consult a physician	Inhalation
Wash with soap and plenty of water. Consult a physician	Skin contact
Flush eyes with water as a precaution	Eye contact
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician	Ingestion

 

5. Firefighting measures

 

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide	Extinguishing media
No data available	Special hazards arising from the substance
Wear self-contained breathing apparatus for firefighting if necessary	Advice for firefighters

 

6. Accidental release measures

 

Use appropriate personal protection equipment (PPE). Wear respiratory protection	Personal precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains	Environmental precautions
Keep in suitable, closed containers for disposal	Methods for containment and cleaning up

 

7. Handling and storage

 

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday	Handling
Keep container tightly closed in a dry and well-ventilated space. Store under inert gas, at room temperature away from light and moisture. Hygroscopic	Storage

 

8. Exposure controls/personal protection

 

Handle in accordance with good industrial hygiene and safety practice	Appropriate engineering controls
Wear suitable protective clothing and gloves	Hand protection
Wear safety glasses with side shields (or goggles) and a face shield	Eye protection
Choose body protection according to the amount and concentration of the dangerous substance at the work place	Skin and body protection
When appropriate, use NIOSH/CEN approved respirator	Respiratory protection

 

9. Physical and chemical properties

 

Liquid	Physical state
Colorless	Color
No data available	Odor
20.03 g/mol	Molecular mass
(6.0 - 8.0 at 25 °C (77 °F	pH
No data available	Relative evaporation rate
(0 °C (32 °F); 3.8 °C (38.8 °F	Melting point
No data available	Freezing point
(100 °C (212 °F) - lit.; 101.4 °C (214.5 °F	Boiling point
No data available	Flash point
No data available	Self ignition temperature
No data available	Decomposition temperature
No data available	(Flammability (solid, gas
No data available	Vapor pressure
No data available	Vapor pressure at 50 °C
No data available	Relative vapor density at 20 °C
No data available	Relative density
1 g/cm3 at 3.98 °C (39.16 °F); 1.10 g/cm3 at 20 °C	Density
Water: Completely miscible	Solubility
No data available	Log Pow
No data available	Log Kow
No data available	Viscosity, kinematic
No data available	Viscosity, dynamic
No data available	Explosive properties
No data available	Oxidizing properties
No data available	Explosive limits

 

10. Stability and reactivity

 

No data available	Reactivity
Stable under recommended storage conditions	Chemical stability
No data available	Possibility of hazardous reactions
Exposure to moisture	Conditions to avoid
Strong oxidizing agents	Incompatible materials
No data available	Hazardous decomposition products

 

11. Toxicological information

 

No data available	Acute toxicity
No data available	Skin corrosion/irritation
No data available	Serious eye damage/irritation
No data available	Respiratory or skin sensitization
No data available	Germ cell mutagenicity
No data available	Carcinogenicity
No data available	Reproductive toxicity
No data available	Specific target organ toxicity - single exposure
No data available	Specific target organ toxicity - repeated exposure
No data available	Aspiration hazard
May be harmful if inhaled. May cause respiratory tract irritation	Symptoms/injuries after inhalation
May be harmful if absorbed through skin. May cause skin irritation	Symptoms/injuries after skin contact
May cause eye irritation	Symptoms/injuries after eye contact
May be harmful if swallowed	Symptoms/injuries after ingestion
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated	Additional information

 

12. Ecological information

 

No data available	Eco toxicity
No data available	Persistence and degradability
No data available	Bio accumulative potential
No data available	Mobility in soil
No data available	Other adverse effects

 

13. Disposal considerations

 

Offer surplus and non-recyclable solutions to a licensed disposal company	Product
Dispose of as unused product	Contaminated packaging

 

14. Transport information

 

ADR/RID:  - IMDG:       - IATA:        -	UN number
ADR/RID: Not dangerous goods IMDG:      Not dangerous goods IATA:        Not dangerous goods	UN proper shipping name
ADR/RID:  - IMDG:       - IATA:        -	(Transport hazard class(s
ADR/RID:  - IMDG:       - IATA:        -	Packaging group
IMDG Marine pollutant:  No ADR/RID:                        No IATA:                                No	Environmental hazards
No data available	Special precautions

 

15. Regulatory information

 

No data available	(Hazard Statements (GHS
No data available	(Precautionary statements (GHS
No data available	National regulations

 

16. Other information

 

The information in this document is based on the best of our knowledge and shall be used only as a guide. The information given is designed for safe use, handling, storage, transportation and disposal. It does not represent any guarantee of the quality of the product

Disclaimer

 

 

Deuterium oxide application: Fiber Optics

Fig 1.Deuterium oxide can be used to manufacture the Fiber Optics

 

The distinctive behavior arising out of the isotope & deuterium bonding effects have found potential use in various industrial scopes. Various applications have been developed in the high tech area using some of the fundamental differences between hydrogen and deuterium.

Optical fibers are widely used when transmitting data over longer distances and at higher bandwidths than traditional copper cables. Replacing the hydrogen with deuterium oxide in the fiber cables reduces the chemical reaction rate leading to deterioration of the light transmission, improves the intensity and transmission characteristics and extends the life of the cable. 

How to create deuterium oxide

Fig 1.Production of deuterium oxide (heavy water) - Girdler sulfide process

As semi heavy water, HDO occurs naturally on Earth in regular water at a proportion of 1 part per 3200, it may be separated from regular water by distillation or electrolysis and also by various chemical exchange processes, all of which exploit a kinetic isotope effect. In short, the difference in mass between the two hydrogen isotopes translates into a difference in the zero-point energy and thus into a slight difference in the speed at which the reaction proceeds. Once HDO becomes a significant fraction of the water, deuterium oxide (heavy water) will become more prevalent as well as water molecules trade hydrogen atoms very frequently. To produce pure deuterium oxide by distillation or electrolysis requires a large cascade of stills or electrolysis chambers, and consumes large amounts of power, so the chemical methods are generally preferred. The most important chemical method is the Girdler Sulfide process.

Source:

https://en.wikipedia.org/wiki/Heavy_water#Production

Manufacturing of duterium lamp using deuterium oxide

Fig 1.Deuterium oxide application: Deuterium lamp manufacturing

 

 

Deuterium lamp (or deuterium arc lamp) is a low-pressure gas-discharge light source often used in spectroscopy when constant and intense ultraviolet light is required.

These light sources utilize a heated tungsten filament that manufactures an arc to the anode in order to energize molecular deuterium for visible and infrared light production.

Arc lamps are remarkable for their high performance in the ultraviolet, with relatively little output in the visible and infrared. Arc lamps made with ordinary light-hydrogen provide a very similar UV spectrum to deuterium, and have been utilized as a part of UV spectroscopes. However, lamps using deuterium have a longer life span and intensity at the far end of their UV range which is three to five times that of a standard hydrogen arc bulb, at the similar temperature. Therefore, Deuterium lamps are considered a superior light source than light-hydrogen arc lamps, for the shortwave UV range.

 

Source:

https://en.wikipedia.org/wiki/Deuterium_arc_lamp

Treatment of semiconductor devices using deuterium oxide

Fig 1.Deuterium oxide can be used to treat semiconductor devices

 

Deuterium oxide or heavy water is used in the production of deuterium gas, a form of naturally occurring pure hydrogen. Chemical formula of deuterium gas is ²H₂ or D₂ and its pure form is rarely seen in the nature.

Deuterium (D₂) and deuterium-substituted gases are used in the manufacture of silicon semiconductors and microchips through the process of deuterium-protium exchange.

Semiconductor device annealing process with deuterium at super atmospheric pressures reduces of the effects of hot carrier stress and improves the operating characteristics. This significantly enhances the life cycle of semiconductors and microchips. It enables chips to be made smaller, have high circuit densities and have a longer life cycle.

 

Source:

https://www.google.com/patents/US6833306

NMR spectroscopy using Deuterium oxide

Fig 1. NMR spectroscopy using Deuterium oxide

The NMR phenomenon is based on the interaction of the nuclei of specific atomic isotopes with a static magnetic field. The utility of NMR arise from the fact that chemically distinct nuclei differ in resonance frequency in the same magnetic field. This phenomenon is known as the chemical shift.

NMR spectroscopy is an essential tool for the determination of molecular structure, the study of molecular dynamics, and the characterization of materials at the molecular level by chemists, physicists, and molecular biologists.

Deuterium oxide (D₂O) is used in nuclear magnetic resonance spectroscopy when using water as solvent if the nuclide of interest is hydrogen. This is because the signal from light water solvent molecules interferes with observing the signal from the molecule of interest dissolved in it.

 

Source:

http://chemnmr.colorado.edu/moreinfo/whatisnmr.html

https://en.wikipedia.org/wiki/Heavy_water

Deuterium oxide vs. deuterium depleted

Unlike deuterium oxide (heavy water) which is a form of water that contains a larger than normal amount of the hydrogen isotope deuterium, Deuterium-depleted water (DDW), also known as light water, has a lower concentration of deuterium than occurs naturally. Deuterium a heavier isotope of hydrogen which has, in addition to its one proton, a neutron, that roughly doubles the mass of the hydrogen atom.

All natural water contains deuterium. Most water contains about 150 ppm. Water with a concentration less than 140 ppm is considered deuterium-depleted. Despite the fact that the consumption of deuterium oxide is harmful, based on clinical studies even seemingly small reduction in deuterium content can improve a number of health parameters in human.

Scientists uncovered that healthy cells react well to reduced amounts of deuterium in water. However, cancer cells are more sensitive to deuterium depletion. Cancer cells, especially tumor cells, cannot adapt rapidly resulting in tumor regression without any side effects on healthy cells. They also studied DDW for metabolic disorders - especially diabetes - with desirable results.

 

Source:

http://www.dancingwithwater.com/deuterium-depleted-water-what-is-it/

https://en.wikipedia.org/wiki/Deuterium-depleted_water

Pharmacological use of deuterium oxide

Fig 1.Development of deuterated drugs using deuterium oxide

 

Deuterium oxide or heavy water is widely used in studies of metabolism of drugs in humans and other animals. Deuterium from deuterium oxide (D₂O) can be exchanged directly into finished drug compounds.

A deuterium containing or deuterated drug is a kind of medicine which one or more of its hydrogen atoms are substituted by deuterium atoms. Metabolic studies have shown that slower metabolism of deuterium containing drugs often allows for longer effective benefit, smaller or less frequent doses and fewer side effects of the drug.

In April 2017 Food and Drug Administration (FDA) approved the first deuterated drug, AUSTEDO™ by Teva (previously referred to as SD-809). Austedo was developed for the treatment of chorea, random involuntary twisting movements, which is associated with Huntington’s disease.

 

Source:

http://www.tevapharm.com/news/teva_announces_fda_approval_of_austedo_deutetrabenazine_tablets_for_the_treatment_of_tardive_dyskinesia_in_adults_08_17.aspx

Core invasion studies using deuterium oxide tracer

Fig 1.Deuterium oxide tracer can be used in oil exploration studies

The main objective of a coring operation is to get accurate information about the oil reservoir. Parameters like oil and water composition determine the saturation levels of a reservoir. Information about the reservoir is evaluated by analysis of the collected cores and samples.

In case of drilling mud core invasion, the recovered liquid does not represent the native liquid but rather a mixture of drilling fluid and reservoir fluid. The amount of coring fluid contamination contained in the formation water of a core sample can be determined using a tracer.

Deuterium oxide or heavy water can be used to trace water base mud systems. Prior to coring a quantity of deuterium oxide is added to the aqueous drilling fluid and samples of the coring fluid taken periodically before, during and after the coring process. The levels of deuterium in the extracted water and coring fluid samples can determine the contamination degree.

?Is drinking deuterium oxide harmful

You may have wondered whether you can you drink heavy water? Is it radioactive? Is it safe?

Deuterium oxide or heavy water is a form of water that contains a larger than normal amount of the hydrogen isotope deuterium, rather than the common hydrogen-1 isotope that makes up most of the hydrogen in normal water. Accordingly, some or most of the hydrogen atoms in deuterium oxide contain a neutron, causing each hydrogen atom to be about twice as heavy as a normal hydrogen atom. The increased weight of the hydrogen in the water thus makes it slightly more dense.

Deuterium oxide is not radioactive. So, if you drink heavy water, you don't have to stress over radiation harming. It's not totally safe to drink, however, because the biochemical reactions in your cells are affected by the distinction in the mass of the hydrogen atoms and how well they shape hydrogen bonds.

If you drank a considerable volume of deuterium oxide, you may feel dizzy because deuterium oxide would change the density of the liquid in your inner ear.

Deuterium oxide damages the ability of mitotic spindles cells to repair their DNA and replicate. If you could replace 25-50% of the regular hydrogen in your body with deuterium, you would encounter issues.

For mammals, replacing 20% of your water with heavy water is survivable; 25% causes sterilization, and about 50% replacement is deadly.

Other species endure deuterium oxide better. For example, algae and bacteria can survive using 100% deuterium oxide.

 

Source:

https://www.thoughtco.com/can-you-drink-heavy-water-607731